Samson did not know that the Lord had departed from him.  Then the Philistines took him and put out his eyes, and brought him down to Gaza.  (Judges 16:20c-21)

Biblically, Gaza is probably best associated with Samson, whom God turned over to his enemies as a result of his inveterate disobedience.

Gaza, עַזָּה or Ghazza, was one of the five city states of Philistia, the ancient kingdom of the Philistines.  And were a thorn in the side of Israel, as seen by God’s reprove of Joshua: